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Biaxin (Clarithromycin)
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Biaxin

Biaxin is a medication of macrolide antibiotics group. Biaxin fights bacteria in the body. Biaxin is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori.

Other names for this medication:
Abbotic, Aeroxina, Biclar, Clacee, Clarimax, Claripen, Clariwin, Clarix, Clonocid, Fromilid, Kalixocin, Karin, Klabax, Klabion, Klarithran, Klerimed, Kofron, Krobicin, Lekoklar, Macladin, Macrobid, Macrol, Moxifloxacin, Preclar, Synclar, Veclam, Zeclar

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Cipro, Zitromax, Erythromycin, Azithromycin, Roxithromycin, Erythrocin, Zmax, Zithromax, Ery-Tab, Dificid, Erythrocin Stearate Filmtab, Eryc, EryPed, Erythrocin Lactobionate, Ilosone, PCE Dispertab

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Also known as:  Clarithromycin.

Description

Biaxin is used to treat many different types of bacterial infections affecting the skin and respiratory system. Biaxin is also used together with other medicines to treat stomach ulcers caused by Helicobacter pylori.

Biaxin fights bacteria in the body.

Biaxin is also known as Clarithromycin, Maclar, Klaricid, Klacid, Clarimac, Claribid.

Dosage

Biaxin is available in tablets.

Take Biaxin orally.

Take Biaxin with full glass of water.

Take Biaxin with or without food.

Do not crush, chew, or break the Biaxin tablet. Swallow the pill whole.

Shake the Biaxin oral suspension well before measuring a dose. Measure the Biaxin oral suspension with a marked measuring spoon or medicine cup.

Take Biaxin for for 7 to 14 days.

The dosage and the kind of medication depend on the disease and its prescribed treatment.

Do not stop taking Biaxin suddenly.

Overdose

If you overdose Biaxin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Biaxin overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Protect from light. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Biaxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Biaxin if you are allergic to its components or to clarithromycin or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), troleandomycin (Tao).

Do not take Biaxin if you're pregnant or you plan to have a baby, or you are a nursing mother.

Do not take Biaxin if you take astemizole (Hismanal), cisapride (Propulsid), ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), or dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), pimozide (Orap), terfenadine (Seldane).

Do not take Biaxin if you have liver disease, kidney disease, myasthenia gravis, porphyria; personal or family history of "Long QT syndrome".

Try to be careful with Biaxin usage in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.

Avoid consuming alcohol.

It can be dangerous to stop Biaxin taking suddenly.

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Although the 2-week regimen of pantoprazole-based triple therapy was effective for H. pylori eradication in clarithromycin-sensitive cases, highly effective H. pylori eradication protocols are needed for clarithromycin-resistant ones.

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In a prospective multicentre study H. pylori was cultivated from biopsies and susceptibility testing was performed according to EUCAST. Resistance to clarithromycin and levofloxacin was determined by sequencing of the resistance-determining regions of 23S rRNA and gyrA genes. cagA, vacA and babA2 genotypes were determined.

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The activity of a new macrolide, TE-031 (A-56268), against Legionella pneumophila in vitro was superior to the activities of roxithromycin, erythromycin and josamycin. The tissue concentrations of TE-031 in guinea pigs after oral administration (20 mg/kg) was much higher than those of roxithromycin, erythromycin and josamycin. The maximum concentration of TE-031 was 107.0 mg/kg in the lung, and 1.4 mg/l in the serum. The uptake of macrolides by cells collected by bronchoalveolar lavage in guinea pigs was measured by a radioisotopic method. The maximum ratios of intracellular to extracellular concentration of TE-031, roxithromycin, josamycin and erythromycin were 71.9, 24.8, 39.7 and 7.9, respectively. In infected guinea pigs, with the exception of erythromycin, the ratios were reduced to approximately half the values in normal animals. TE-031 showed greater therapeutic efficacy against experimental L. pneumophila pneumonia than roxithromycin, erythromycin and josamycin. TE-031 is a promising drug for treatment of legionella pneumonia and should be investigated in a clinical study on human Legionnaires' disease.

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To systematically review the efficacy and tolerance of moxifloxacin-based triple therapy, and to conduct a meta-analysis of studies comparing this regimen with clarithromycin-based triple therapy.

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Three-day treatment with azithromycin 500 mg once daily is equivalent to a 10-day treatment with clarithromycin 500 mg twice daily in adult patients with AECB.

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To evaluate the efficacy of sequential vs hybrid therapy in patients with Helicobacter pylori (H. pylori) infection.

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Because Helicobacter pylori creates a well-sheltered microenvironment within the gastric mucus layer, it has been speculated that the disruption of this space by a mucolytic agent may enhance the eradication rate. The aim of the present study was to investigate the effect of erdosteine, a strong mucolytic agent, on the effectiveness of PPI-based, first-line triple therapy in the eradication of H. pylori.

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Of 286 children with confirmed nontuberculous mycobacteria infection, 14 (4.9%; median age 50 mos, range 9-156 mos; 5 [36%] male, 9 [64%] female) had nontuberculous mycobacteria facial skin lesions. Six (43%) had lesions on the cheek and five (36%) in the medial eye corner. Polymerase chain reaction results confirmed the presence of Mycobacterium haemophilum in eight patients (57%) and Mycobacterium avium in six patients (43%). The facial lesions were treated using a combination of clarithromycin and rifabutin for 12 weeks, with a median healing time of 4 months.

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The overall healing rate (per protocol) at five weeks (116/128) was 90.6% while in 85.5% (65/76) eradication was successful. The healing rate for the H. pylori eradicated patients (58/65) was 89.2%. For those who failed eradication (8/11) it was 72.7% (NS), while for patients not infected with H. pylori at entry to the study (50/52) it was 96.2% (NS). An intention to treat analysis showed that after 20 weeks of omeprazole prophylaxis with the 10mg dose 86% (43/50) had maintained healing while for the 20mg dose a similar figure was observed (87.9; 58/66). Only three patients in the two groups (pp) had persistent H. pylori infection, all of whom relapsed. No patients discontinued treatment because of adverse effects of the drugs.

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biaxin brand name 2016-04-09

The optimal therapy for Helicobacter pylori (H. pylori) infection should combine a high cure rate and a short treatment duration with a favorable side-effect profile Pinamox Caps 500 Mg Amoxicillin And Alcohol and should maintain a low cost. Several strategies have been proposed to increase the H. pylori eradication rate, including the extension of the treatment duration to 14 d, the use of a four-drug regimen (quadruple, sequential, and concomitant treatments), and the use of novel antibiotics, such as levofloxacin. However, triple therapy remains the most widely accepted first-line treatment regimen in Brazil and the United States and throughout Europe. Because this therapy is limited by resistance to clarithromycin, other therapeutic regimens have been investigated worldwide. This review describes the current literature involving studies directly comparing these different therapies and their efficacies.

biaxin xl filmtab 2015-06-03

The resistance rate was 80% for metronidazole and 4% for clarithromycin. Tetracycline and amoxycillin showed very low degree of resistance with 1 (0.4%) and 3 (1.3%) of the strains resistant to these antibiotics, respectively. Age Cefpodoxime 100mg Tablets , sex and ethnicity had a remarkable effect on the resistance rate.

biaxin storage 2017-10-12

Tuberculosis dactylitis is well tolerated for a long time Macrol Tablet leading to a late diagnosis which may favour its spreading. Antituberculosis treatment is effective but the functional outcome depends on early diagnosis.

biaxin xl clarithromycin and alcohol 2016-06-12

We conducted a clinical Cefuroxime Zinacef Dose study to evaluate a new method of treatment for persistent inflammation after AOM in children.

biaxin usual dosage 2017-06-25

Sarcoidosis is recognized as Myclav 625 Tablet a multiorgan disorder characterized by the presence of non-caseating granulomas in the involved tissues. It has been suggested that sarcoidosis might be due to the exposure to infectious or non-infectious agents in genetically susceptible individuals. In particular, Propionibacterium acnes and Mycobacterium tuberculosis have been considered causative microorganisms. We report a case of P. acnes-associated sarcoidosis in which a drastic improvement was achieved with clarithromycin administration. A possible mechanism of clarithromycin action is discussed.

biaxin pill images 2016-10-25

The eradication Megamox 457 Mg Dose rate for the traditional standard therapy was 68.9%, and adding the probiotic "Bifidus infantis" to triple therapy, led to a successful rate of eradication of 83% (P < 0.001). Pre-treatment with 2 weeks of B. infantis before adding it to standard triple therapy increased the success rate of eradication to 90.5%. Similar improvement in eradication rate was noted when B. infantis was added as an adjuvant to the sequential therapy leading to an eradication rate of 90.8%.

biaxin allergy to penicillin 2016-03-16

The occurrence of clarithromycin resistance among Helicobacter pylori strains is a major cause of the treatment failure. Resistance to this drug is conferred by point mutations in 23S rRNA gene and the most prevalent mutations are A2143G and A2142G. The aim of the study was to evaluate the occurrence of A2143G and A2142G Klimicin Medicine mutations in a group of H. pylori strains resistant to clarithromycin.

biaxin alcohol a comprehensive view 2015-03-05

Peptic ulcer rebleeding does not occur in patients with complicated ulcers after H. pylori eradication. Maintenance anti-ulcer (antisecretory) therapy is Cefuroxime Axetil 250 Mg Uses not necessary if eradication is achieved.

biaxin antibiotic side effects 2017-07-05

A case of severe thrombocytopenic purpura is described in a 56-year-old female following Helicobacter pylori eradication therapy consisting of omeprazole, clarithromycin and amoxycillin. The pathogenesis of this patient's thrombocytopenia appears to be quite complex. Whilst it was clearly triggered by antibiotic treatment, a direct toxic mechanism does not provide an adequate explanation for the severity and lack of responsiveness to drug treatment. It is tempting to suggest that an immunological mechanism and splenomegaly were also involved.