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Cleocin (Clindamycin)

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Generic Cleocin is a high-quality medication which is taken in treatment of serious infections caused by certain bacteria. Generic Cleocin acts by stopping the production of essential proteins needed by the bacteria to survive.

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Also known as:  Clindamycin.


Generic Cleocin is a perfect remedy in struggle against serious infections caused by certain bacteria.

Generic Cleocin acts by stopping the production of essential proteins needed by the bacteria to survive.

Cleocin is also known as Clindamycin, Clindatec, Dalacin, Clinacin, Evoclin.

Generic name of Generic Cleocin is Clindamycin Capsules.

Brand name of Generic Cleocin is Cleocin.


Take Generic Cleocin orally with or without food.

Take Generic Cleocin with a full glass of water.

Use Generic Cleocin at the same time each day.

Do not stop taking Generic Cleocin suddenly.


If you overdose Generic Cleocin and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Generic Cleocin if you are allergic to Generic Cleocin components or to to tartrazine.

Be very careful if you're pregnant or you plan to have a baby, or you are a nursing mother.

Try to be very careful with Generic Cleocin if it is given to children younger than 10 years old who have diarrhea or an infection of the stomach or bowel. Elderly patient should use Generic Cleocin with caution.

Be sure to use Generic Cleocin for the full course of treatment.

Avoid alcohol.

It can be dangerous to stop Generic Cleocin taking suddenly.

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Cell culture infection experiments revealed that all tested antibiotics reduced bacterial numbers within infected osteoblasts when treatment was started immediately, whereas some antibiotics lost their activity against intracellular persisting bacteria. Only rifampicin almost cleared infected osteoblasts in the acute and chronic stages. Furthermore, we detected that low concentrations of gentamicin, moxifloxacin and clindamycin enhanced the formation of SCVs, and these could promote chronic infections. Next, we treated a murine osteomyelitis model in the acute and chronic stages. Only rifampicin significantly reduced the bacterial load of bones in the acute phase, whereas cefuroxime and gentamicin were less effective and gentamicin strongly induced SCV formation. During chronicity none of the antimicrobial compounds tested showed a beneficial effect on bone deformation or reduced the numbers of persisting bacteria.

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To evaluate the safety and efficacy of an abbreviated course of antibiotic therapy in postpartum endomyometritis, 109 patients with endomyometritis were randomized to three study groups. All were treated with clindamycin and tobramycin until afebrility and clinical signs of disease were absent. Patients in group I received antibiotics for greater than or equal to 24 hours, group II received therapy for greater than or equal to 48 hours, and group III received antibiotic therapy for greater than or equal to 48 hours that preceded a 7-day course of oral Augmentin. The groups were similar in size and in demographic and clinical parameters. Two patients from each group required a third antibiotic, and no patient required rehospitalization. Group III required more days of antibiotic therapy than did group I, 2.9 versus 2.1 days (p less than 0.01), and cost $412.00 more per patient. This data strongly suggest that a short course of antibiotic therapy is efficacious and safe and would result in substantial monetary savings.

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The in vitro activity of the ester Ro 41-3399 and its free active acid Ro 40-6890 was tested against 189 strains of anaerobic bacteria in comparison to other oral cephalosporins and to antimicrobial agents established in the treatment of anaerobic infections. Prevotella, Porphyromonas, Peptostreptococcus, Fusobacterium and Clostridium spp. were susceptible to Ro 40-6890, with few exceptions. Due to its lack of activity against the major pathogens of the Bacteriodes fragilis group, Ro 40-6890 does not promise to be of major use in the treatment of infections caused by anaerobes.

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Infections of methicillin-resistant Staphylococcus aureus (MRSA) are becoming an increasingly concerning clinical problem. The aim of this study was to assess the development of MRSA in urine cultures in a major public university-affiliated hospital and the therapeutical and hygiene-related possibilities for reducing resistance.

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An antibiotic-sensitivity study was conducted on 117 strains of group A streptococcus (GAS), 60 strains of group G streptococcus (GGS) and 20 strains of group C streptococcus (GCS) in order to understand current resistance trends.

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Six patients with pseudomembranous colitis unrelated to lincomycin or clindamycin treatment were investigated for signs of localised or diffuse cytomegalovirus (CMV) infection. Before the onset of colitis 3 patients had receive prednisone, associated in 2 of them with immunosuppressive drugs. Testing for CMV included rectal mucosa biopsies, culture of blood leucocytes with human embryo diploid fibroblasts in continuous layer and titration of complement-deviating anti-CMV antibodies. Cytomegalic cells with nuclear inclusion bodies were found in the rectal mucosa of 5 patients, 4 of whom also had foci of CMV-infected cells in leucocyte-fibroblast cultures, indicative of viraemia. The fifth patient was not tested for viraemia but developed very high anti-CMV antibodies titers at a later stage. These results show that pseudomembranous colitis that are not due to antibiotics are frequently associated with localised or diffuse CMV infection. Viral invasion of the colon might be encouraged by a state of immunodeficiency.

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Clinicians are not always aware of current clinical guidelines, and dentists and physicians exhibit different patterns regarding antibiotic prescribing. Dentists are more familiar than physicians with current protocols of the AHA.

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The activity of the new streptogramin RP 59500 in vitro was determined against 380 strains of anaerobic bacteria by an agar dilution method and compared with that of pyostacine, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole and chloramphenicol. RP 59500 and imipenem were the most active agents tested. On the basis of these results, RP 59500 appears to be a promising antimicrobial agent for treatment of anaerobic infections, further clinical investigations being warranted.

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Texas Children's Hospital, Houston, TX; inpatients and outpatients with community-acquired infection.

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Objective. A combination of intravenous clindamycin and oral tetracycline has been used for many years as a treatment for active rheumatoid arthritis (RA), despite the absence of good evidence for its efficacy. A single-blind pilot study of this therapy suggested that a double-blind placebo-controlled trial was warranted. Methods. Patients with active RA were randomised in a 2 : 1 ratio to receive active treatment or placebo for 25 weeks. The active treatment consisted of intravenous clindamycin in a reducing regime, and oral tetracycline twice daily three times a week. 50 patients were to be recruited. The primary outcome measure was the proportion of patients achieving an ACR20 response. Results. An interim statistical analysis was performed after 20 patients had completed the study. Two patients in the active group achieved an ACR20 response, with none in the placebo group (NS). There was a better ESR20 response in the placebo group (P = .02). There were no other significant differences between the groups. The results indicated that it was unlikely that a significant difference in ACR20 response would emerge if the remaining 30 patients were recruited. The trial was therefore halted. Conclusion. This antibiotic regime is unlikely to be a valuable therapy for active rheumatoid arthritis.

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Bacterial vaginosis, the most common infectious cause of vaginitis, is characterized by a shift in normal vaginal flora from predominantly aerobic to mainly anaerobic flora. Incidence rates in various studies have ranged from 1-0-45%. Unclear are both the pathophysiology of the observed reduction in lactobacilli and whether bacterial vaginosis is sexually transmitted. Evidence for sexual transmission is provided by a significantly greater incidence of bacterial vaginosis in women with more than 5 sexual partners compared to those in a lifelong monogamous relationship, while bacterial detection in virgins and the failure to demonstrate benefits of partner treatment argue against sexual transmission. Use of an IUD does appear to be a risk factor. The only symptom consistently reported by women with bacterial vaginosis is a malodorous vaginal discharge; however, over half of women with this condition are asymptomatic. The standard criterion for diagnosis includes the presence of 3 of the following signs: the clue cell, homogeneous discharge that adheres to but is easily wiped off the vaginal wall, an elevated vaginal pH, and the potassium hydroxide test for volatile amines. Of concern is the potential for serious sequelae. The abnormal bacterial flora associated with vaginosis significantly impede the white blood cell response to infection. Gynecologic-obstetric sequelae include pelvic inflammatory disease, endometritis, postoperative vaginal cuff infections, preterm labor, premature rupture of membranes, and chorioamnionitis. Metronidazole and clindamycin are the most effective treatment agents. Given the long-term risks associated with bacterial vaginosis, a full course of antibiotics should be considered in both obstetric patients with this condition and women undergoing outpatient ambulatory invasive surgical procedures.

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Although the exact role of quorum sensing (QS) in various stages of biofilm formation, maturation, and dispersal and in biofilm resistance is not entirely clear, the use of QS inhibitors (QSI) has been proposed as a potential antibiofilm strategy. We have investigated whether QSI enhance the susceptibility of bacterial biofilms to treatment with conventional antimicrobial agents. The QSI used in our study target the acyl-homoserine lactone-based QS system present in Pseudomonas aeruginosa and Burkholderia cepacia complex organisms (baicalin hydrate, cinnamaldehyde) or the peptide-based system present in Staphylococcus aureus (hamamelitannin). The effect of tobramycin (P. aeruginosa, B. cepacia complex) and clindamycin or vancomycin (S. aureus), alone or in combination with QSI, was evaluated in various in vitro and in vivo biofilm model systems, including two invertebrate models and one mouse pulmonary infection model. In vitro the combined use of an antibiotic and a QSI generally resulted in increased killing compared to killing by an antibiotic alone, although reductions were strain and model dependent. A significantly higher fraction of infected Galleria mellonella larvae and Caenorhabditis elegans survived infection following combined treatment, compared to treatment with an antibiotic alone. Finally, the combined use of tobramycin and baicalin hydrate reduced the microbial load in the lungs of BALB/c mice infected with Burkholderia cenocepacia more than tobramycin treatment alone. Our data suggest that QSI may increase the success of antibiotic treatment by increasing the susceptibility of bacterial biofilms and/or by increasing host survival following infection.

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cleocin 600 mg po 2017-09-11

Symptomatic relapse of Clostridium difficile toxin-associated colitis occurred in three patients with ovarian cancer. In two patients, C difficile toxin-positive diarrhea initially appeared in association with antibiotic therapy. The third patient developed diarrhea after chemotherapy, without recent antecedent antibiotic administration. Patients were initially treated with oral Septra 800 160 Mg metronidazole and became asymptomatic and toxin-negative. A symptomatic toxin-positive recurrence then developed after the subsequent course of systemic chemotherapy. Recurrent C difficile toxin-associated colitis or pseudomembranous colitis after chemotherapy has not been reported previously in the gynecologic oncology literature. Clostridium difficile-induced diarrhea must be considered in chemotherapy patients with diarrhea because management concepts vary from those for noninfectious diarrhea.

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Coagulase-positive staphylococci (CPS) cause staphylococcal food poisoning. Recently, these bacteria have received increasing attention due to their potential role in the dissemination of antibiotic resistance markers. The present study aimed to evaluate coagulase-positive staphylococci counts, species distribution, enterotoxin genes prevalence, and the antibiotic resistance profile of CPS isolated from in natura chicken meat. Fifteen frozen and 15 chilled industrialized, uncooked chicken parts or entire carcasses were used. Staphylococcal counts revealed that frozen chicken meat samples displayed the lowest CPS count compared with chilled chicken meat samples (p<0.01). Staphylococcus aureus (62%) was the most common species, followed by S. intermedius, S. delphini Vandazole With Alcohol , and S. schleiferi subsp. coagulans (10% each) and S. hyicus (8%). The polymerase chain reaction identification of sea, seb, sec, sed, and see genes revealed that 70% of the isolates harbored at least one enterotoxin gene, with sea and sed being the most frequently encountered ones. Two of the 50 investigated strains harbored three different enterotoxin genes. A high frequency of isolates resistant to penicillin, teicoplanin, oxacillin, and clindamycin was observed, and 80% of CPS were found to be resistant to at least one of the 11 tested antimicrobials. Vancomycin-resistant S. aureus and S. intermedius showed minimum inhibitory concentrations of 512 and 64 μg/mL, respectively. These isolates might indicate the dissemination of vancomycin resistance in the community and imply food safety hazards.

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Among strains tested, 95 (39%) were erythromycin resistant. Twenty-six (10.7%) isolates were D-test positive (iMLS(B) phenotype), 41 (16.88%) were constitutively resistant (cMLS(B) phenotype), and 28 isolates (11.52%) were found to be negative by D-test. The incidence of both inducible and constitutive phenotypes was higher in MRSA isolates compared to methicillin-sensitive S. aureus (MSSA) Para Que Sirve El Metronidazol Flagenase 500 Mg isolates.

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More sophisticated knowledge of the microbiologic components of pelvic infection, the availability of several new antimicrobial agents, and pressures to control medical costs are contributing to changes in antibiotic prescribing patterns in hospitals in the US. The use of prophylactic antibiotics is the area that has undergone the greatest change in Amoxidin 7 500 Mg the field of obstetrics and gynecology. Prophylactic antibiotics are widely administered after cesarean section to prevent postpartum soft tissue infections. The combination of clindamycin and an aminoglycoside, or single-agent therapy with a newer cephalosporin or penicillin, results in a higher success rate than the previous regimen of penicillin G and an aminoglycoside. Women given prophylactic antibiotics in conjunction with vaginal hysterectomy also demonstrate a reduced incidence of postoperative uterine infections; in abdominal hysterectomy, the utility of this approach is not as obvious. For patients with pelvic infections, those with early infection (symptoms for 4 days or less and no indurated mass) are more likely to be cured by antibiotics and less likely to require operative intervention than those with more advanced infection. The selection of antibiotic in cases of pelvic infection should be based on the susceptibility patterns of the organism and the antibiotic's ability to reduce high counts of anaerobic bacteria. Both metronidazole and clindamycin meet these criteria.

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Root canal infections are usually caused by a mixture of two or three species of bacteria. Specific kinds of antibiotic Omnix 200 Mg Tablet can be selected to control these bacterial infections after antibiotic sensitivity testing.

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To retrospectively review Is Biaxin A Sulfa Based Drug trends in clindamycin resistance among Staphylococcus aureus head and neck abscesses between January 2000 and June 2008.

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In 50 patients, 48-hour double-probe pH monitoring was Clendix 500 Mg performed in postoperative of laringectomy, after a intraoperatory placement. Descriptive analysis of 4 variables of pH to level of the sensor proximal, and definition of the presence of esofagic reflux and LPR.

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We reviewed data on the treatment of bacterial vaginosis published from 1989 through 1992 (articles published after the 1989 publication of the Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines). This review suggests that oral metronidazole (500 mg twice daily for 7 days) is the Buy Ultraquin Online preferred treatment for bacterial vaginosis. Other effective (but alternative) treatment regimens include single-dose metronidazole (2 g orally), 2% clindamycin vaginal cream (once daily for 7 days), 0.75% metronidazole vaginal gel (twice daily for 5 days), and oral clindamycin (300 mg twice daily for 7 days). Data do not support the practice of routine treatment of male sex partners of infected females. Treatment of bacterial vaginosis during pregnancy should focus on the elimination of symptoms; data on adverse pregnancy outcomes for women with bacterial vaginosis remain insufficient to recommend treatment of asymptomatic patients. Before performing surgical abortion, treatment of bacterial vaginosis (symptomatic or asymptomatic) should be considered to prevent pelvic inflammatory disease.

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To evaluate the in Tab Combutol vitro activity of daptomycin against 2679 Gram-positive cocci.